Amino Acids

Amino acids are the building blocks of proteins and are also used by the cell as neurotransmitters, sources of energy and in a variety of other processes. The a-amino acids all have the same basic structure shown below, where the R-group is the portion that is unique for each amino acid. They are called a amino acids, because an amino group is attached to the carbon next to (alpha to) the carboxylic acid group. The table below contains a list of amino acids, abbreviations, side chain pKA values and complete structures.

Name Abbreviations Structure pKA1
3 letter 1 letter
Nonpolar
Alanine Ala A
Leucine Leu L
Valine Val V
Isoleucine Ile I
Proline Pro P
Methionine Met M
Phenylalanine Phe F
Tryptophan Trp W
Polar, uncharged
Glycine Gly G
Serine Ser S
Threonine Thr T
Asparagine Asn N
Glutamine Gln Q
Acidic
Aspartic acid Asp D 4.4
Glutamic acid Glu E 4.4
Cysteine Cys C 8.5
Tyrosine Tyr Y 10.0
Basic
Lysine Lys K 10.0
Arginine Arg R 12.0
Histidine His H 6.5

1These are pKA values that are commonly found for these side chains when they are part of a protein. The pKA values for these side chains may be quite different for the free amino acid in solution.

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