Welcome students and Friends!
My name is Dr. Paul A. Craig and I am a Professor of Biochemistry and Bioinformatics at the Rochester Institute of Technology located in Rochester, NY. Use the navigation on the top to visit my other sections and to find out information.In the Lab
Dr. Laura Tubbs and I co-direct a proteomics lab at RIT. We are looking for markers from a soil bacterium, Pseudomonas putida KT2440, that are generated in response to known carcinogens such as 2-naphthylamine. At the same time, we are using a proteomics approach to identify proteins that are expressed in response to compounds that give false positive (caffeine), false negative (diethylstylbesterol) results with the Ames test.Simulations
I am quite interested in developing interactive computer programs that simulate separations processes encountered in biochemistry and proteomics. To date we have developed simulations of ion exchange chromatography, one dimensional electrophoresis and two dimensional electrophoresis.Ionex is available as , a standalone Windows application or one of three tabs in the java-based JBioFramework application. You can use the 1D electrophoresis simulation from the 1DE simulation web site or as one of three tabs in the java-based JBioFramework application. Our most recent development is a simulation of 2D electrophoresis which is currently available as one of three tabs in the java-based JBioFramework application. If you are interested in helping with development of these tools or creating class or lab exercises with these tools, please email me. We are hoping to get the source code up on Sourceforge.net to simplify collaboration.
